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Esomeprazole decreases the amount of acid produced in the stomach. Esomeprazole is used to treat ulcers, gastroesophageal reflux disease (GERD or heartburn), erosive esophagitis, and other conditions involving excessive stomach acid production. Esomeprazole may also be used for purposes other than those listed in this medication guide.

HOW TO TAKE THIS MEDICATION
Take esomeprazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass (8 ounces) of water. Esomeprazole should be taken at least one hour before a meal. Follow your doctor's instructions. Do not break or chew the capsules. Swallow them whole. They are specially formulated to release slowly in the body. If you have difficulty swallowing the capsules, one tablespoon of applesauce can be added to an empty bowl and the esomeprazole capsule can be opened, and the pellets inside the capsule carefully emptied onto the applesauce. The pellets should be mixed with the applesauce and then swallowed immediately. The applesauce should not be hot and should be soft enough to be swallowed without chewing. The pellets should not be chewed or crushed. The pellet / applesauce mixture should not be stored for later use. Do not stop taking esomeprazole even if you begin to feel better. Your symptoms may improve before the condition is fully treated. Store esomeprazole at room temperature away from moisture and heat.

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NEXIUM is for the treatment of frequent, persistent heartburn symptoms due to acid reflux disease. These symptoms typically occur on 2 or more days per week despite treatment and diet change.

For many people, NEXIUM can also heal damage to the esophagus caused by acid reflux. This damage can occur over time, when acid from the stomach erodes (wears away) the lining of the esophagus. Only a doctor can determine if you have this condition, called erosive esophagitis. Most erosions heal in 4 to 8 weeks. Your results may vary.

Side effects with NEXIUM include headache, diarrhea, and abdominal pain. Symptom relief does not rule out other serious stomach conditions.

MISSED DOSE
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

OVER DOSE
Seek emergency medical attention. Symptoms of an esomeprazole overdose include:

drowsiness
shortness of breath
tremor
loss of coordination
seizures
SIDE EFFECTS
If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking esomeprazole and seek emergency medical attention. Other, less serious side effects may be more likely to occur. Continue to take esomeprazole and talk to your doctor if you experience:

headache
diarrhea
nausea
flatulence
abdominal pain or constipation
dry mouth.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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